Glossary

Akinesia The absence of movement
Basal Ganglia A large group of nuclei deep within the brain that affects movement. The basal ganglia include the caudate nucleus, putamen, globus pallidus, subthalamic nucleus, and substantia nigra.
Blood Brain Barrier A protective barrier that allows only certain substances to enter the brain from blood vessels
Bradykinesia Slowness in performing movements
Chorea Ongoing, rapid, and irregular flitting movements of the body that appear willful, but are involuntary
Dopamine Agonist A drug that binds primarily with dopamine receptors and mimics the action of dopamine
Dyskinesia Abnormal involuntary movements that typically are medication induced
Dystonia Involuntary twisting of the body due to abnormal muscle contractions
Enzyme Proteins that serve as catalysts for biochemical reactions within the brain
Essential Tremor The most common form of tremor, which typically begins in adolescence and young adulthood and becomes more pronounced in middle to advanced years, i.e., after age 50. It comprises a single symptom such as uncontrollable shaking of the head, hands, arms, or other part of the body, which stops when at rest. The condition is often hereditary.
Festinating Gait Involuntary acceleration of one's gait
Hypomimia A mask-like face with little expression
Levodopa (L-Dopa) The chemical precursor to dopamine in the brain; also the most common and most effective agent for managing symptoms of Parkinson's disease.
Lewy Bodies Eosinophilic structures with a dense protein core found in the cytoplasm of pigmented neurons; a pathological marker of Parkinson's disease when found within the substantia nigra.
Micrographia Handwriting that decreases in size
Neurotransmitters Chemicals that transmit nerve impulses across a space (or synapse) from one nerve to another
Receptor A structure on the surface of a cell that selectively binds with substances such as neurotransmitters and hormones
Striatum A mass of grey matter that includes the putamen and caudate
Substantia Nigra Dopamine-producing nerve cells located in the brain stem that control voluntary movement
Synapse The junction between two nerve cells, or neurons
   

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